Due to significant differences across species in liver pathways, in vitro models of the human liver are being increasingly utilized to screen for the potential efficacy, metabolism and/or toxicity of candidate compounds. Cultures of primary human hepatocytes (PHHs) are widely considered to be the ‘gold standard’ for creating such models.
Watch our webinar for a comprehensive overview of various models that one may apply to hepatocytes from the very basic to complex.
Topics:
- Reveal tips and best practices for the short-term and long-term culture of primary human hepatocytes (PHHs)
- Discuss the utility of PHH cultures for assessing drug clearance, drug metabolite identification, drug-transporter interactions, etc.
- Suggest product solutions where appropriate
Webinar Speaker:
- Salman Khetani, Ph.D., Associate Professor, Bioengineering, University of Illinois at Chicago, USA
