Originally recorded on 14 March 2018
at the Society of Toxicology Meeting in San Antonio, TX, USA.
In this online symposium Drs. Jessica Hartman and Martin Phillips present 2D and 3D models being developed by ScitoVation for assessing hepatotoxicity. By combining Lonza’s primary hepatocytes and liver non-parenchymal cells in 2D or 3D models, the viability, phenotypic behavior, and response of cells to chemicals is enhanced.
This webcast explores how scientists can improve the physiological relevance of their in vitro liver models, while ensuring the complexity of cultures is kept to a minimum, saving laboratories both time and money.
Topics covered include
- Hepatocytes as a metabolically active, in vitro test system
- Comparison of existing technologies
- Alginate encapsulation for testing slowly-cleared chemicals
- Development of 2D and 3D organotypic rat liver models
Speakers
- Jessica Hartman, PhD Director of Cell-Based Assay Development ScitoVation
- Dr. Martin Phillips Manager, Biokinetics and Biosimulations Division ScitoVation
- Dr. Maureen Bunger Product Manager – ADME/Tox Solutions Lonza
