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Overall potential benefits of endotoxin automation with the PyroTec® PRO System

The PyroTec® PRO System not only can improve your lab's efficiency but also elevate your compliance standards. By implementing Lonza's automation solution, you significantly reduce the potential for human error, while enhancing the accuracy, reliability, and traceability of your test results.


Discover how Lonza worked with medical device company Ethicon to successfully justify and implement PyroTec® Pro Automated Robotic Solution.

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Improve quality

  • Enhanced QC control: The PyroTec® PRO System empowers you with precise control, ensuring the highest quality standards.
  • Minimize manual errors: Automation reduces the risk of human mistakes, which provides more reliable and consistent results.
  • Boost reproducibility: Achieve improved levels of reproducibility in your tests, creating a robust foundation for your laboratory's success.

Prepare for the future

  • Scalability: Adapts to your business growth and changing demands.
  • Efficiency redefined: Realize greater testing efficiency, allowing your lab to handle more samples with ease and precision.
  • Sustainability: Compatible with a sustainable test method that align with your sustainability goals.

Save precious time

  • Streamlined training: Reduce the training burden on your staff as PyroTec® PRO simplifies complex processes into intuitive automation.
  • Decrease revalidation requirements: Save time and resources by minimizing revalidation needs, allowing you to focus on essential tasks.
  • Boost productivity: Free up your team's valuable time for more critical tasks while PyroTec® PRO handles the repetitive work efficiently.
  • Maintain workflow: Seamlessly integrate automation into your existing workflows, ensuring a smooth transition without disruptions.

The PyroTec® PRO System
 

The PyroTec® PRO System is designed to accommodate both rFC (Recombinant Factor C Assay | Lonza) and Kinetic LAL reagents (chromogenic and turbidimetric), providing flexibility to cater to all your sample testing needs. Additionally, the integration of Lonza's WinKQCL® Analysis and Detection Software (Endotoxin Detection and Analysis Software | Lonza) ensures a complete solution that streamlines methods, devices, training, data management, auditing, trending, and servicing for your endotoxin testing program, now and in the future.

Ready to embark on the journey of automated endotoxin testing? Contact us today, and let us show you how BET automation with the PyroTec® PRO System can elevate your laboratory's capabilities and outcomes.

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Implementation

Our trained and certified engineers perform the system IQOQPQ following a specific sequence governed by controlled documentation for the building, testing and qualification of the mechanical, electronic and software components:

Once on site, engineers uncrate and assemble the robot which is followed by IQ and OQ testing of the performance of the readers and robotic system components. The PyroTec® PRO System configuration specific for the endotoxin automation application (kinetic LAL automation and/or rFC automation) commences with IQOQPQ of the on deck devices and labware. The robotic arm movements are fine-tuned to enable optimal alignment and performance. A standardized PQ assay protocol is conducted to test the full functionality of the system for each assay method for BET automation.

It is recommended that you prepare your own PQ protocol for endotoxin automation based on knowledge of the types of samples to be tested and the results obtained by the current manual BET method.

The PyroTec® PRO System is both simple to operate and to maintain. Users carry out a few simple procedures, through the WinKQCL® Software, at specified intervals to ensure efficient daily operation. The system can be protected by purchasing a Lonza maintenance contract that provides for both routine annual maintenance and emergency call out in the event of breakdown. Troubleshooting and support is accessed through our trusted Scientific Support Team.

Building a business case

Lonza can assist evaluation of a customer’s current workflow using return on investment (ROI) modelling to support business case proposal for endotoxin automation with the PyroTec® PRO System. Details such as sample throughput, repeat testing rates, shift rotations, methods in use, sample types and manipulations required and future growth will all influence a successful ROI determination. Aspects such as enhanced data integrity, reduction in repetitive strain injury risk, and simplified end user training needs should also be considered as part of any business case for endotoxin automation.

The example in the table highlights the estimated time-savings that can be achieved by endotoxin automation with the Lonza PyroTec® PRO Automated Robotic Solution.

 

*This table illustrates the estimated time-savings, reduction in repeat testing rate and consumables cost savings for a laboratory testing 20,000 water samples per annum using a manual kinetic chromogenic plate-based method including interference controls (positive product control, PPC) with each sample. The Return on Investment for this example is 1.9 years, well below the typically targeted 3 year ROI.

Let us answer your questions

We realize the budget process requires ample justification for your investment in endotoxin automation; our sales team are available to help support and justify your time and monetary investment.

Let’s see how automation will improve your endotoxin testing program, together.

Please contact our Scientific Support Team to start exploring a business case for endotoxin automation in your organization.

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