Stellate Cells, Human Cryopreserved, 1 Million Cells
Stellate Cells, Human Cryopreserved, 1 Million Cells
Low passage stellate cells dervied from human liver tissue containing 1 million cells/vial.
Do you need a modified version of this cell product, such as different vialing sizes, or isolations from special donors or species? Contact Lonza CellBio Services to discuss custom isolation, expansion, and testing options for your research
You May Also Need...
Product Overview
Stellate cells are a resident cell type of the liver primarily functioning to store retinoids. In response to liver damage, stellate cells rapidly lose the stored retinoids and differentiate into a proliferating fibroblast-like cell that begins depositing collagen matrix. This activity causes buildup of collagen in the liver eventually leading to cirrhosis.
Stellate cells can be isolated from liver tissue, enriched, and placed into cell culture. When placed into culture, stellate cells begin to immediately differentiate into the activated state, characterized by high expression of alpha-smooth muscle actin, a-SMA.
Human Stellate Cells are stellate cells enriched from human liver isolations and grown to >80% confluency and then cryopreserved.
Human Stellate Growth Medium (Catalog MST-500BK) is available to support optimal culture health and growth characteristics of stellate cells.
Characterization performed:
- Post-thaw plating to observe characteristic stellate morphology.
- Flow cytometry using antibodies for Vimentin Immunocytochemistry for a-SMA
Benefits
Low passage for high activation potential
Characterized for alpha-SMA
Applications
- ADMETox
- Disease research
Storage and Content
Cryopreserved Cells, 1 million viable cellsSDS, CoA, and Instructions
Safety Data Sheets (SDS)
Choose a language to view the SDS.
Certificate of Analysis (CoA)
Please enter Lot Number, including all zeros, located on the product label and please take into account that it is case sensitive.
Educational Material
Brochures, White Papers etc.
-
Primary Human Hepatocyte 3D Spheroids Co-cultured with Non-Parenchymal Cells
High Throughput Meets Physiological Relevence -
Advanced hepatic cell culture techniques
Drug-Induced Liver Injury (DILI) toxicology modeling throughout the discovery pipeline -
Validating a high throughput co-culture of hepatocytes and non-parenchymal cells: Bringing physiological relevance to screening applications
