H-RPE – Human Retinal Pigment Epithelial Cells
What You May Also Need
The retinal pigment epithelium (RPE) consists of pigmented cells situated between the neuroretina and the choroids. The RPE is comprised of hexagonal cells organized into a monolayer that is densely packed with pigment granules. The RPE is of the neuroectodermal origin and is therefore considered to be part of the retina. RPE cells play a critical role in visual function and photoreceptor viability.
Lonza's Human RPE cells are cryopreserved, primary RPE cells that are packaged at passage 2 and contain ≥500,000 cells per vial. HRPE are guaranteed through 5 population doublings and stain positive (≥90%) for pancytokeratin and Zo-1 and negative (≤10%) for fibroblast contamination and endothelial marker CD31 ( ≤1%). They also test negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis (CoA) is provided for with cell lot purchased.
- Age-related macular degeneration
- Retinitis pigmentosa
- Diabetic retinopathy
- Photoreceptor degeneration
- Gene expression
- Cellular interactions
Content & Storage
1 x Cryopreserved Ampule with ≥500,000 cells/vial