Recombinant
Factor C assay

For over 30 years, you have relied on Lonza for our bacterial endotoxin test (BET) expertise. But we know that science is never finished. Our commitment to sustainability drives us forward, motivated by figuring out something that no one has before.

Worldwide, there is a growing appeal in the pharmaceutical industry for recombinant technologies that help alleviate, and eventually replace, the use of animal resources for endotoxin testing purposes. Adoption of recombinant test methods, like the PyroGene® rFC assay, are on the rise. Increased use of recombinant methods has proven their equivalency to LAL-based methods and, therefore, increased confidence in implementing rFC methods in QC testing labs.

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Benefits of the rFC assay

With the recombinant Factor C Assay, you can meet the demands of endotoxin testing while protecting a natural resource. You can also realize the immediate benefits from using recombinant reagents including batch-to-batch consistency and security of supply, all while moving toward your sustainability and future-proofing goals. Together, we safely bring your next medicine to life.

For a detailed product overview, educational materials, and scientific data about the effectiveness of rFC as a BET assay, please visit the PyroGene^® rFC Product Page.

At Lonza, we are committed to protecting the welfare of the horseshoe crab through adopting best practices and actively supporting conservation efforts. Learn more about Lonza's conservation efforts on our Endotoxin Testing page.

Automated set-up of the PyroGene^® rFC Assay on the ASSIST PLUS

Application note

This application note describes how the manual pipetting steps of the PyroGene® rFC Assay can be semi-automated with Integra’s ASSIST PLUS pipetting robot.

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RecombinantFactor C assay

Benefits of the rFC assay

Automated set-up of the PyroGene® rFC Assay on the ASSIST PLUS

Recombinant
Factor C assay

Automated set-up of the PyroGene^® rFC Assay on the ASSIST PLUS