Vaccine Manufacturing … Creating Immunity to Fight Off Diseases
Vaccine manufacturing has been widely popular ever since Pasteur developed the rabies vaccine in 1885. Since then vaccine manufacturing has continued to be popular due to the defense that vaccines provide against certain viruses. The human immune system is constantly defending itself against a barrage of viruses and we simply lack the capacity to recognize and fight against these ever changing pathogens. Vaccines are designed to help mobilize the host’s immune system to prevent virus infections and break the chain of transmission.
Vaccine development and manufacturing has led to vaccines against Hepatitis A and B, influenza, measles, mumps and polio just to name a few. Immunizations have helped many childhood diseases that caused a large number of deaths historically, to be extremely rare with only a few or no cases a year.
Tactics for vaccine manufacturing rely on two main types of vaccines:
- Active immunity: Induced after injecting of a modified version or part of the pathogen into the recipient by stimulating an immune response against the infectious agent. This provides long term protection from the virus in question.
- Passive immunity: Induced after injecting antibodies or secondary agent directed against the pathogen into the recipient. While this is a short term protection from the pathogen, depending on the virus this may be all that is needed.
Vaccine manufacturing relies on processing a virulent parental virus in four different ways: