Control Standard Endotoxin for PYROGENTTM Gel Clot LAL Assays
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Gel Clot LAL (PYROGENTTM) provides a simple positive/negative result and is most often mentioned in pharmacopeial monographs as the official referee test. Lonza’s PYROGENTTM Gel Clot LAL Assay is a qualitative LAL test for Gram-negative bacterial endotoxin. The gel clot assay is run in tubes that are placed in a water bath or dry heat block at 37°C. After a one-hour incubation period, the tubes are flipped 180°. A firm clot that stays in the bottom of the tube indicates a positive reaction. If liquid flows down the side of the tube, the result is negative for endotoxin. PYROGENTTM Gel Clot LAL Assay requires depyrogenated 10 x 75 mm glass reaction tubes to run the assay.
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