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Pharma & Biotech

InMyoFib – Human Intestinal Myofibroblasts

Catalog #: CC-2902

Cryopreserved ampule of Human Intestinal Myofibroblasts (InMyoFib) containing ≥500,000 cells 

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Product Overview

Lonza offers Human Intestinal Myofibroblasts (H-InMyoFib), cryopreserved at passage 2 with ≥500,000 cells per vial. H-InMyoFibs share phenotypic characteristics of both fibroblasts and smooth muscle cells but do not express smooth muscle markers such as smoothelin, caldesmon, or (in the normal colon and small intestine) desmin. They play a fundamental role in growth and development of intestine, immunology, inflammation, fibrosis, water and electrolyte transport, contraction and wound healing.

Cryopreserved CloneticsTM Human Intestinal Myofibroblasts (H-InMyoFib) are guaranteed through 15 population doublings, express alpha SM Actin after thaw ≥70% and Desmin ≤10%. All cells test negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis is provided for each cell lot purchased.

Recommended Medium: SMGMTM-2 BulletKitTM

Benefits

  • Absorption studies & toxicology pertaining to oral medications  
  • Inflammation
  • Fibrosis  
  • Water & electrolyte transport
  • Contraction & peristalsi  
  • Wound healing
  • Neoplasia & intestinal polyp formation  
  • Crohn’s disease  
  • Toxicology and cytotoxicity
  • Gene expression

 

Content & Storage

Content

1 x Cryopreserved ampule InMyoFib containing ≥500,000 cells 

Instructions

Safety Data Sheets (SDS)

Certificate of Analysis (CoA)

Please enter Lot Number, including all zeros, located on the product label and please take into account that it is case sensitive.

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