InMyoFib – Human Intestinal Myofibroblasts
Cryopreserved ampule of Human Intestinal Myofibroblasts (InMyoFib) containing ≥500,000 cells
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Product Overview
Lonza offers Human Intestinal Myofibroblasts (H-InMyoFib), cryopreserved at passage 2 with ≥500,000 cells per vial. H-InMyoFibs share phenotypic characteristics of both fibroblasts and smooth muscle cells but do not express smooth muscle markers such as smoothelin, caldesmon, or (in the normal colon and small intestine) desmin. They play a fundamental role in growth and development of intestine, immunology, inflammation, fibrosis, water and electrolyte transport, contraction and wound healing.
Cryopreserved CloneticsTM Human Intestinal Myofibroblasts (H-InMyoFib) are guaranteed through 15 population doublings, express alpha SM Actin after thaw ≥70% and Desmin ≤10%. All cells test negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis is provided for each cell lot purchased.
Recommended Medium: SMGMTM-2 BulletKitTM
Benefits
- Absorption studies & toxicology pertaining to oral medications
- Inflammation
- Fibrosis
- Water & electrolyte transport
- Contraction & peristalsi
- Wound healing
- Neoplasia & intestinal polyp formation
- Crohn’s disease
- Toxicology and cytotoxicity
- Gene expression
Content & Storage
Content
1 x Cryopreserved ampule InMyoFib containing ≥500,000 cells
