3D Cell Culture

Interpreting the physiological relevance of cell culture model systems is a challenging goal. Typical 2-dimensional (2D) static cell culture models are missing factors such as 3-dimensional (3D) tissue structures and fluid flow that cells are significant functional drivers of cell behavior in vivo. As a consequence, static 2D cell cultures are many times poor predictors of in vivo cell behavior and association of this cell behavior with disease, drug efficacy, and toxicity outcomes.

Developing 3D cell culture models that are fit-for-purpose requires consistent, time-tested building blocks. Lonza provides these key building blocks with our RAFT^TM 3D Cell Culture and Quasi Vivo^® Systems, each backed by years of research and development. Supported by dozens of peer-reviewed publications, these technologies are ready-to-use saving time and resources normally needed for internal engineering.

Combined with our large portfolio of primary cells and supporting media, Lonza has all you need to develop the right 3D cell culture system to advance your research.

For more information:

RAFT^TM 3D Cell Culture System

The RAFT^TM System is a simple-to-use 3D cell culture system that enables the production of robust, reproducible 3D cultures in less than an hour. It creates cell cultures inside a high-density collagen scaffold that more closely mimics the natural environment of cells.

Quasi Vivo^® 3D Cell Culture System

Quasi Vivo^® Systems are a series of advanced interconnected cell culture flow systems that enables addition of media perfusion to existing monolayer and 3D cell culture models. By mimicking in vivo interstitial fluid flow, Quasi Vivo^® Systems provide cells with continuous levels of nutrients and waste removal leading to improved phenotypes and better longevity in culture.

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3D Cell Culture

RAFTTM 3D Cell Culture System

Quasi Vivo® 3D Cell Culture System

RAFT^TM 3D Cell Culture System

Quasi Vivo^® 3D Cell Culture System