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Human Hepatocytes in Disease Modeling
Description
Hepatocyte Formats
Recommended Catalog Numbers
Hepatitis infection model
A process in which primary human hepatocytes are infected with the hepatitis virus for drug screening or biomarker discovery/development
Highest quality plated monolayer cultures
3D cultures/Spheroids
Co-Cultures
Malaria parasite infection model
A process in which primary human hepatocytes are infected with Plasmodium falciparium varieties for drug screening or biomarker discovery/development
Highest quality plated monolayer cultures
3D cultures/Spheroids
Co-Cultures
Non-alcoholic steatohepatitis (NASH) models
Steatosis can be induced in hepatocytes using a variety of small molecule or nutrient inducers.
Highest quality plated monolayer cultures
3D cultures/Spheroids
Co-Cultures
Diabetes models
Hepatocytes respond to insulin by altering their glucose and fat metabolism. Various assays to induce lipogenesis and gluconeogenesis in hepatocytes are used.
Highest quality plated monolayer cultures
3D cultures/Spheroids Co-Cultures