Human Liver-Derived Endothelial Cells P1
Human Liver-Derived Endothelial Cells P1
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Product Overview
Endothelial cells are the primary barrier cells that line blood vessels and sinusoids of the liver. Human Liver-derived Endothelial Cells (HLECs) are isolated and enriched from liver tissue, then cryopreserved for use in a wide range of research models. A unique subtype of LECs, liver sinusoidal endothelial cells, are defined as a subset of cells found at the interface between the liver sinusoids and hepatocytes.
HLECs derived from whole livers lead to a mixed population of vascular endothelial cells and sinusoidal endothelial cells. HLECs characterized for markers of endothelial cells, including vWF maintain appropriate endothelial morphology over limited serial passaging. Measurement of uptake of acetylated LDL as well as CD32b to indicate percentage of the sinusoidal endothelial cell population. The recommended medium for HLECs is EGMTM 2 which is optimized for endothelial cell health and growth.
Request More InfoBenefits
- Low passage
- Verified for large molecule uptake
Storage and Content
Cryopreserved Cells, >1 Million viable cellsSDS, CoA, and Instructions
Safety Data Sheets (SDS)
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Certificate of Analysis (CoA)
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Instructions for Use - Hepatocyte and Non-Parenchymal Cell (NPC) 2D Co-Culture
Protocol for 2D co-culture of human hepatocytes and non-parenchymal cells -
Hepatocytes and Non-parenchymal Cells - Development and Optimization of a Comprehensive Co-Culture
Tech Note detailing the development of a co-culture protocol for Heps and NPCs -
3D Spheroid Primary Human Hepatocyte and Non-Parenchymal Cell (NPC) Co-Culture - Instructions for use
