REGM™ Renal Epithelial Cell Growth Medium BulletKit™
REGM™ Renal Epithelial Cell Growth Medium BulletKit™
Culture system containing REBMTM Basal Medium (CC-3191) and REGMTM SingleQuotsTM supplements (CC-4127) required for growth of
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Product Overview
REGMTM Renal Epithelial Cell Growth Medium is formulated to maintain and expand most renal epithelial cells. REGMTM contains 0.5% serum.
Select References:
- Diabetic Nephropathy is a chronic, progressive renal disease/diabetic kidney disease that develops in approximately one third of people with diabetes. In a study, Lonza’s human proximal tubular epithelial cells were cultured in respective media (REGMTM). The group investigated the role of KLK1 (kallikrein) in tubular pro-inflammatory responses in cultured human RPTEC and examined the role of PAR-4 (Protease-Activated Receptor 4) activation in KLK1-mediated signaling in the development of DN. Yiu WH, Wong DW, Chan LY, Leung JC, Chan KW, Lan HY, Lai KN, Tang SC. Tissue Kallikrein Mediates Pro-Inflammatory Pathways and Activation of Protease-Activated Receptor-4 in Proximal Tubular Epithelial Cells. PLoS ONE (2014); 9(2): e88894
- Renal Graft Research: In vitro renal epithelial cell culture models have provided a great deal of information about the outcome of renal clinical transplantation models. In a study carried out using Lonza’s Primary Human Renal Proximal Tubular Epithelial cells maintained in REGMTMTM renal epithelial growth media (cat# CC-2553 & CC-3190 respectively), the group study the effects of HCMV (Human cytomegalovirus) infection on renal cells. Masako Shimamura, Joanne E. Murphy-Ullrich and William J. Britt. Human Cytomegalovirus Induces TGF-β1 Activation in Renal Tubular Epithelial Cells after Epithelial-to-Mesenchymal Transition. PLoS Pathogens. (2010); 6(11): e1001170
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Storage and Content
1 x REBMTM Basal Medium (CC-3191), 500 mL
1 x REGMTM SinglequotsTM Supplement Pack (CC-4127) containing:
1 x Green Cap Vial with hEGF, 0.50 mL
1 x Lilac Cap Vial with Insulin, 0.50 mL
1 x Natural Cap Vial with Hydrocortisone, 0.50 mL
1 x Red Cap Vial with GA-1000, 0.50 mL
1 x Bottle FBS, 2.50 mL
1 x Natural Cap Vial with Transferrin, 0.50 mL
1 x Amber Vial with Triiodothyronine, 0.50 mL
1 x Amber Vial with Epinephrine, 0.50 mL
SDS, CoA, and Instructions
Safety Data Sheets (SDS)
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Certificate of Analysis (CoA)
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TechSheet - Renal Epithelial Cell Systems
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Instructions - Renal Cell Systems
Instructions for culturing Clonetics™ Human Renal Cells
Educational Material
Brochures, White Papers etc.
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Epithelial Cells Concentration Guide
Epithelial cell culture media guide with SingleQuots® concentration.