NHCF-V – Human Ventricular Cardiac Fibroblasts
Cryopreserved ampule of Normal Human Ventricular Cardiac Fibroblasts (NHCF-V) containing ≥ 500,000 cells
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Product Overview
Human Cardiac-Related Fibroblasts include Aortic Adventitial Fibroblasts (AoAF) isolated from the tunica external of the ascending or descending aorta and cardiac fibroblasts (NHCF-A and -V) isolated from the atrium or ventricle. Cells are isolated from normal, adult heart tissue. Cryopreserved cells are shipped at passage 2.
CloneticsTM NHCF-V & -A are guaranteed through 5 population doublings and express ≥90% collagen I and ≤10% Von Willibrand factor VIII after thaw. CloneticsTM AoAF are guaranteed through 10 population doublings and are negative for alpha smooth muscle actin. All cells test negative for mycoplasma, bacteria, yeast and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis (CoA) is provided for each cell lot purchased.
Benefits
- Assured for experimental use up to 15 population doublings
- Express ≥90% collagen I and ≤10% Von Willibrand factor VIII
- All cells test negative for mycoplasma, bacteria, yeast, and fungi
- HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots
- Certificate of Analysis provided for every cell lot
Applications
- Vascular diseases
- Neointimal formation
- Vascular remodeling
- Atherosclerosis
- Hypertension
- Myocardial repair
- Extracellular maintenance during cardiac cell / tissue growth
- Cardiac Fibrosis Paracrine signalling
- Toxicology
- Gene expression
Content & Storage
Content
1 x Cryopreserved ampule NHCF-V containing ≥ 500,000 cells/vial