Product Overview

Stem cells possess the unique ability to proliferate as an undifferentiated cell type, then, when properly stimulated, differentiate into multiple lineages of cells. Lonza’s TheraPEAK^® MSCGM^TM Mesenchymal Stem Cell Medium is a serum-free medium designed to proliferate human bone marrow derived mesenchymal cells in an undifferentiated state. The medium has been specifically designed and tested to ensure that the medium neither promotes spontaneous differentiation of cells nor inhibits cell differentiation to osteogenic, chondrogenic, or adipogenic lineages (when properly stimulated with an appropriate differentiation media). Serum-free media, such as TheraPEAK^® MSCGM^TM Mesenchymal Stem Cell Medium, are intended to support cell growth without serum supplementation. Lonza's TheraPEAK^® MSCGM^TM Mesenchymal Stem Cell Medium is of primary interest to those seeking maximal control over research and manufacturing variables.  TheraPEAK^®  MSCGM^TM Mesenchymal Stem Cell Medium does not contain phenol red or antibiotics.

Partial List of Cells Proliferated with TheraPEAK^® MSCGM^TM Mesenchymal Stem Cell Medium*:

• Human bone marrow derived stem cells
• Human periodontal ligament derived stem cells
• Human adipose derived stem cells

TheraPEAK^®  MSCGM^TM Mesenchymal Stem Cell Medium is offered as a BulletKit^®  Medium (catalog no. BEBP18-936) which includes both the basal media and the necessary supplements for proliferation of human bone marrow derived mesenchymal stem cells. The basal medium (MSCBM Mesenchymal Basal Medium; catalog no. BEBP12-934Q) and the necessary supplements (MSCGM^TM SingleQuots^TM Kit ; catalog no. BP13-935J) can also be purchased individually.

*List of cells generated from customer data. Lonza only routinely uses this medium with Lonza’s human bone marrow derived mesenchymal stem cells and can therefore only guarantee the successful use of this media with these cells All TheraPEAK^®  Media are GMP products intended to support further manufacturing and are produced to GMP raw material standards. These media products conform with cGMP manufacturing compliance expectations for medical devices including 21 CFR Part 820 and ISO 13485. TheraPEAK^®  Media products are produced at FDA registered manufacturing sites with an ISO 13485 certified quality management system.  All research use only formulations are produced according to ISO:9001.