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Silensomes™ CYP Phenotyping Kit.

Silensomes™ CYP Phenotyping Kit.

Catalog #: SIL-MCPNL

SilensomesTMCYP Phenotyping Kit. Human liver microsomes preinhibited for easy, reproducible results.

 

Note:  This product to be discontinued following depletion of current inventory.  Please contact Wepredic directly for future needs

 

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Product Overview

SilensomesTM are validated human pooled liver microsomes (HLM) chemically and irreversibly inactivated for one specific CYP using mechanism based inhibitors (MBI). Contents of the CYP Phenotyping Kit include 7 individual SilensomesTM HLM inhibited for CYP2C9, CYP1A2, CYP2B6, CYP2A6, CYP2D6, CYP2C8, and CYP3A4 P450s, plus the SilensomesTM Master Control.

Format:

Each specific CYP SilensomesTM HLM is supplied in 150 μL as 20mg/mL microsomal protein with matched Control SilensomeTM HLM (batch dependent) that was treated under the exact same conditions without inhibitor. 

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Benefits

  • Minimal off target effects
  • Directly quantitative P450 reaction phenotyping
  • Prevalidated for minimal user effort
  • Ready to use

Applications

  • Cytochrome P450 Reaction Phenotyping

Storage and Content

1 X SilensomesTM CYP3A4 HLM
1 X SilensomesTM CYP1A2 HLM
1 X SilensomesTM CYP2A6 HLM
1 X SilensomesTM CYP2B6 HLM
1 X SilensomesTM CYP2D6 HLM
1 X SilensomesTM CYP2C8 HLM
1 X SilensomesTM CYP2C9 HLM
1 X Master Control SilensomesTM HLM

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SDS, CoA, and Instructions

Safety Data Sheets (SDS)

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Certificate of Analysis (CoA)

Please enter Lot Number, including all zeros, located on the product label and please take into account that it is case sensitive.

  • Instructions - Silensomes™ CYP Phenotyping Kit

    Technical information and instructions for using Silensomes™ CYP Phenotyping Kits
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Educational Material

Brochures, White Papers etc.

  • Product Sheet - Silensomes™ CYP Phenotyping Kits

    Introducing Silensomes™ CYP Phenotyping Kits – A New Approach for P450 Phenotyping Assays
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Hepatocyte and Related Product Information Request

Information or Quote Request

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