The ToxiLightTM Non-destructive Cytotoxicity Bioassay Kit Is a bioluminescent cytotoxicity bioassay designed to measure toxicity in mammalian cells and cell lines in culture. The kit is based on the bioluminescent measurement of adenylate kinase (AK) which is present in all cells. A loss of cell integrity, through damage to the plasma membrane, results in the leakage of a number of factors from cells cultured in vitro into the surrounding medium.
The measurement of the release of AK from the cells allows for the accurate and sensitive determination of cytotoxicity and cytolysis. Unlike many other cytotoxicity assays, the ToxiLightTM BioAssay Kit does not destroy cells, so it is possible to take repeated samples of the culture medium without disrupting the cell culture to analyze the kinetics of cell death.
To learn more and request further information, visit the ToxiLightTM Non-destructive Cytotoxicity Bioassay Kit product page.