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From LAL to rFC Assay

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Article overview

Comparing endotoxin testing results of modern recombinant to traditional LAL methods

Learn about Jay Bolden and co-workers extensive study of peer-reviewed literature to find publications where naturally contaminated samples were tested side by side  (same samples, only difference being the test method, i.e. rFC vs LAL/TAL).

Confidence for adopting the rFC method in your lab

Different aspects of the endotoxin testing are considered to shed some light on articles that question the use of rFC for release testing.

Recombinant factor C adopted into Ph. Eur.

During the last session of the European Pharmacopoeia Commission, endotoxin testing with rFC was adopted as general chapter 2.6.32. 

 

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