Human Cryo Kupffer Cells, 0.2 Million
Human Cryo Kupffer Cells, 0.2 Million
Naïve Kupffer cells derived from human liver tissue. 0.2 million cells per vial
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Product Overview
Kupffer cells are the resident macrophages in the liver and are part of the first line of defense against bacteria and toxins in the gut. Kupffer cells exhibit typical macrophage morphology and can be activated to produce inflammatory cytokines, growth factors and reactive oxygen species.
In vivo, prolonged activation of Kupffer cells are associated with many diseases of the liver including Non-alcoholic Fatty Liver Disease (NAFLD), Non Alcoholic Steato Hepatitis (NASH), and liver damage associated with certain bioactivated chemicals. Human Cryopreserved Kupffer cells are isolated and enriched from dissociated human liver tissue and then cryopreserved as passage 0. Characterization of isolated Kupffer cells includes assessing morphology in plated format and evaluating functional responses to LPS stimulation.
Request More InfoBenefits
- LPS Inducible
- High activation potential
- Naïve primary cells - never has contacted plastic dish
Applications
- ADMETox
- Disease research
Storage and Content
Cryopreserved Cells, > 200K viable cellsSDS, CoA, and Instructions
Safety Data Sheets (SDS)
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Certificate of Analysis (CoA)
Please enter Lot Number, including all zeros, located on the product label and please take into account that it is case sensitive.
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Instructions - Cryopreserved Kupffer Cells
Instructions for Thawing and Plating of Human Cryopreserved Kupffer Cells -
Instructions for Use - Hepatocyte and Non-Parenchymal Cell (NPC) 2D Co-Culture
Protocol for 2D co-culture of human hepatocytes and non-parenchymal cells -
Hepatocytes KC Cell Co-Culture Protocol
