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Silensomes™ CYP Phenotyping Kit.

Silensomes™ CYP Phenotyping Kit.

Catalog #: SIL-MCPNL

SilensomesTMCYP Phenotyping Kit. Human liver microsomes preinhibited for easy, reproducible results.

 

Note:  This product to be discontinued following depletion of current inventory.  Please contact Wepredic directly for future needs

 

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 3’329.00 CHF
SA

Product Overview

SilensomesTM are validated human pooled liver microsomes (HLM) chemically and irreversibly inactivated for one specific CYP using mechanism based inhibitors (MBI). Contents of the CYP Phenotyping Kit include 7 individual SilensomesTM HLM inhibited for CYP2C9, CYP1A2, CYP2B6, CYP2A6, CYP2D6, CYP2C8, and CYP3A4 P450s, plus the SilensomesTM Master Control.

Format:

Each specific CYP SilensomesTM HLM is supplied in 150 μL as 20mg/mL microsomal protein with matched Control SilensomeTM HLM (batch dependent) that was treated under the exact same conditions without inhibitor. 

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Benefits

  • Minimal off target effects
  • Directly quantitative P450 reaction phenotyping
  • Prevalidated for minimal user effort
  • Ready to use

Applications

  • Cytochrome P450 Reaction Phenotyping

Storage and Content

  • 1 X SilensomesTM CYP3A4 HLM
    1 X SilensomesTM CYP1A2 HLM
    1 X SilensomesTM CYP2A6 HLM
    1 X SilensomesTM CYP2B6 HLM
    1 X SilensomesTM CYP2D6 HLM
    1 X SilensomesTM CYP2C8 HLM
    1 X SilensomesTM CYP2C9 HLM
    1 X Master Control SilensomesTM HLM

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SDS, CoA, and Instructions

Certificate of Analysis (CoA)

Please enter Lot Number, including all zeros, located on the product label and please take into account that it is case sensitive.

  • Instructions - Silensomes™ CYP Phenotyping Kit

    Technical information and instructions for using Silensomes™ CYP Phenotyping Kits
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Educational Material

Brochures, White Papers etc.

  • Product Sheet - Silensomes™ CYP Phenotyping Kits

    Introducing Silensomes™ CYP Phenotyping Kits – A New Approach for P450 Phenotyping Assays
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Hepatocyte and Related Product Information Request

Information or Quote Request

Request information or quote for hepatocytes, SilensomesTM  HLM, or NoSpin HepaRGTM cells and media here.

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