Cell migration can sometimes be destructive, which is known as cell invasion. This is defined as the movement of cells through a three-dimensional (3D) matrix, and includes attachment to, as well as degradation and restructuring of the matrix components. Cancer cells often display invasion-type movement through the extracellular matrix (ECM). As such, by mimicking this process in cell-based invasion assays, it is possible to reveal the cell migration mechanisms underlying tumor formation and metastasis, as well as inform the development of novel cancer therapies.
You can also learn more about the CytoSMARTTM System on the product page, including how its real-time and label-free live-cell imaging capabilities enables the capture of dynamic cellular processes while minimizing the risk of side effects from dyes, markers or reporter genes.