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Pharma & Biotech

Human Hepatocytes, Cryopreserved Plateable and Metabolism Qualified

Catalog #: HUCPM

Cryopreserved Human Hepatocytes, Plateable, Metabolism Qualified are specifically pre tested for metabolic activity of CYP2C9, CYP2D6, and CYP3A4.

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Product Overview

Cryopreserved Human Hepatocytes, Plateable, Metabolism Qualified are specifically pre tested for metabolic activity of CYP2C9, CYP2D6, and CYP3A4. They are tested for healthy morphology lasting 72 hours in culture. Metabolism Qualified hepatocytes are ideal for shorter-term plated hepatocyte applications, such as 24 hour metabolic clearance assays and genomics applications. The General Purpose hepatocytes should not be used in drug-drug interaction studies. For drug-drug interaction studies, please refer to the Induction Qualified hepatocytes (HUCPI)

Benefits

  • Precharacterized for appropriate hepatocyte morphology
  • Large inventory of multiple donors
  • precharacterized for CYP3A4, CYP2C9, and CYP2D6 mediated drug clearance in plated format

Applications

  • Low clearance metabolism studies
  • Short term toxicity testing
  • Genomics

Content & Storage

Content

Cryo Vial, >5 million viable cells

Instructions

Safety Data Sheets (SDS)

Certificate of Analysis (CoA)

Webinar -Hepatocytes in the Drug Development Pipeline

Overview of how primary hepatocytes are used in drug development

Human Hepatocyte Inventory

Human

Inventory

View donor information and select characteristics of currently available human hepatocyte lots. Table includes single donor and pooled donor lots in either suspension or plateable formats

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1+1=3: Buy two vials of cryopreserved hepatocytes, get the third free.

End of Year Promotion

For a limited time, buy 2 vials of cryopreserved primary human or animal hepatocytes and receive a 3rd vial for free. Terms and conditions apply.

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