Silensomes™ CYP Phenotyping Kit.
Silensomes™ CYP Phenotyping Kit.
SilensomesTMCYP Phenotyping Kit. Human liver microsomes preinhibited for easy, reproducible results.
Note: This product to be discontinued following depletion of current inventory. Please contact Wepredic directly for future needs
Product Overview
SilensomesTM are validated human pooled liver microsomes (HLM) chemically and irreversibly inactivated for one specific CYP using mechanism based inhibitors (MBI). Contents of the CYP Phenotyping Kit include 7 individual SilensomesTM HLM inhibited for CYP2C9, CYP1A2, CYP2B6, CYP2A6, CYP2D6, CYP2C8, and CYP3A4 P450s, plus the SilensomesTM Master Control.
Format:
Each specific CYP SilensomesTM HLM is supplied in 150 μL as 20mg/mL microsomal protein with matched Control SilensomeTM HLM (batch dependent) that was treated under the exact same conditions without inhibitor.
Request More InfoBenefits
- Minimal off target effects
- Directly quantitative P450 reaction phenotyping
- Prevalidated for minimal user effort
- Ready to use
Applications
- Cytochrome P450 Reaction Phenotyping
Storage and Content
1 X SilensomesTM CYP3A4 HLM
1 X SilensomesTM CYP1A2 HLM
1 X SilensomesTM CYP2A6 HLM
1 X SilensomesTM CYP2B6 HLM
1 X SilensomesTM CYP2D6 HLM
1 X SilensomesTM CYP2C8 HLM
1 X SilensomesTM CYP2C9 HLM
1 X Master Control SilensomesTM HLM
SDS, CoA, and Instructions
Certificate of Analysis (CoA)
Please enter Lot Number, including all zeros, located on the product label and please take into account that it is case sensitive.